Acetic Acid

Acetic Acid

SCHEMBL8471925

CC(=O)O.CCCCCCC1CCC(=O)O1

nearest known ligand 0.84

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.84
PPARG P37231 2/20 0.56
PRKCA P17252 4/20 0.44
EPHX1 P07099 1/20 0.43
GRM2 Q14416 3/20 0.42
ALDH1A1 P00352 1/20 0.42
POLB P06746 1/20 0.41
FASN P49327 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113200 0.92 CYP1A2 (1.00) CYP1A2PPARGPRKCAEPHX1GRM2
SCHEMBL113498 0.92 CYP1A2 (1.00) CYP1A2PPARGPRKCAEPHX1GRM2
SCHEMBL333202 0.92 CYP1A2 (1.00) CYP1A2PPARGPRKCAEPHX1GRM2
SCHEMBL3661965 0.92 CYP1A2 (1.00) CYP1A2PPARGPRKCAEPHX1GRM2
SCHEMBL2077607 0.92 CYP1A2 (1.00) CYP1A2PPARGPRKCAEPHX1GRM2
SCHEMBL7054931 0.92 CYP1A2 (1.00) CYP1A2PPARGPRKCAEPHX1GRM2
SCHEMBL7059195 0.92 CYP1A2 (1.00) CYP1A2PPARGPRKCAEPHX1GRM2
SCHEMBL8210280 0.92 CYP1A2 (1.00) CYP1A2PPARGPRKCAEPHX1GRM2
SCHEMBL17627672 0.92 CYP1A2 (1.00) CYP1A2PPARGPRKCAEPHX1GRM2
SCHEMBL7059128 0.92 CYP1A2 (1.00) CYP1A2PPARGPRKCAEPHX1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5948812-A ORDORANTS GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 1999-09-07 US disclosed