Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 17/20 | 0.57 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473947 | 0.92 | ESR1 (0.58) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL8473855 | 0.91 | ESR1 (0.55) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL14503731 | 0.90 | ESR1 (0.53) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL5419421 | 0.89 | ESR1 (0.53) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL1359801 | 0.87 | ESR1 (0.56) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL5430797 | 0.87 | ESR1 (0.58) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL7107781 | 0.87 | ESR1 (0.60) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL1358515 | 0.86 | ESR1 (0.63) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL8475241 | 0.86 | ESR1 (0.57) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL1359583 | 0.86 | ESR1 (0.57) | ESR1ESR2PSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958916-A | FOR INHIBITING BONE LOSS OR BONE RESORPTION | ELI LILLY AND COMPANY (US) | 1999-09-28 | — | — | US | disclosed |