Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474906 | 0.83 | KMT2A (0.56) | USP2L3MBTL1HSD17B10CYP2D6TSHR | |
| SCHEMBL8475416 | 0.81 | MEN1 (0.59) | L3MBTL1HSD17B10CYP2D6TSHRALDH1A1 | |
| SCHEMBL18159900 | 0.79 | USP2 (0.69) | USP2L3MBTL1HSD17B10CYP2D6TSHR | |
| SCHEMBL22354498 | 0.79 | USP2 (0.75) | USP2L3MBTL1HSD17B10CYP2D6TSHR | |
| SCHEMBL709506 | 0.78 | USP2 (1.00) | USP2L3MBTL1HSD17B10CYP2D6TSHR | |
| SCHEMBL19060953 | 0.78 | USP2 (0.67) | USP2L3MBTL1HSD17B10CYP2D6TSHR | |
| SCHEMBL5481687 | 0.78 | HSD17B10 (0.61) | USP2L3MBTL1HSD17B10ALDH1A1ATM | |
| SCHEMBL10949734 | 0.77 | USP2 (0.41) | USP2L3MBTL1HSD17B10CYP2D6TSHR | |
| SCHEMBL8475076 | 0.77 | MEN1 (0.36) | USP2CYP2D6TSHRATMSMN1; SMN2 | |
| SCHEMBL734049 | 0.77 | USP2 (0.72) | USP2L3MBTL1HSD17B10CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012071102-A2 | BUFFER COMPOUNDS | SACHEM, INC. (US) | 2012-05-31 | — | — | WO | disclosed |
| US-20120129240-A1 | BUFFER COMPOUNDS | SACHEM, INC. | 2012-05-24 | — | — | US | disclosed |