Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 5/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | MTTP | P55157 | 6/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | APOB | P04114 | 4/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.35 |
| ▸ | MICA | Q29983 | 2/20 | 0.35 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473353 | 0.84 | CD274 (0.42) | PRMT5WDR77CD274DRD2DRD3 | |
| SCHEMBL8472709 | 0.84 | ACACB (0.46) | PRMT5WDR77DRD3ACACBTNF | |
| SCHEMBL8473015 | 0.84 | CD274 (0.42) | PRMT5WDR77CD274DRD2DRD3 | |
| SCHEMBL8470382 | 0.84 | ACACB (0.40) | PRMT5WDR77CD274DRD2DRD3 | |
| SCHEMBL8472897 | 0.84 | ACACB (0.45) | PRMT5WDR77CD274DRD2DRD3 | |
| SCHEMBL8474536 | 0.84 | CD274 (0.42) | PRMT5WDR77CD274DRD2DRD3 | |
| SCHEMBL8473578 | 0.84 | ACACB (0.47) | DRD3ACACBTNFNOD2NOD1 | |
| SCHEMBL8470379 | 0.84 | ACACB (0.43) | PRMT5WDR77CD274DRD2DRD3 | |
| SCHEMBL8475446 | 0.84 | TNF (0.49) | DRD2DRD3ESR1ESR2KMT2A | |
| SCHEMBL8473166 | 0.83 | PRMT5 (0.38) | PRMT5WDR77CD274DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919795-A | ATHEROSCLEROSIS THERAPY | PFIZER INC. (US) | 1999-07-06 | — | — | US | claimed |