Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 7/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474374 | 0.83 | DRD3 (0.48) | DRD2ALDH1A1ALOX15DRD3DRD5 | |
| SCHEMBL8474247 | 0.81 | MEN1 (0.40) | ALDH1A1 | |
| SCHEMBL8475696 | 0.79 | POLB (0.44) | DRD2ALDH1A1DRD3DRD5HPGD | |
| SCHEMBL8471273 | 0.79 | MEN1 (0.38) | ALDH1A1ALOX15HTR7 | |
| SCHEMBL6774683 | 0.78 | DRD3 (0.55) | DRD2ALDH1A1DRD3DRD5HTR7 | |
| SCHEMBL8475156 | 0.76 | MEN1 (0.39) | ALDH1A1PTGS2 | |
| SCHEMBL6769609 | 0.71 | DRD3 (0.66) | DRD2ALDH1A1DRD3DRD5HTR7 | |
| SCHEMBL6775180 | 0.67 | DRD3 (0.56) | DRD2ALDH1A1DRD3DRD5HTR7 | |
| SCHEMBL6505674 | 0.67 | KDM4E (0.58) | DRD2ALDH1A1DRD3HTR1A | |
| SCHEMBL8854901 | 0.66 | KDM4E (0.50) | DRD2ALDH1A1ALOX15DRD3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962448-A | Pyrroloazepine derivatives | SUNTORY LIMITED (JP) | 1999-10-05 | — | — | US | disclosed |