Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481459 | 0.88 | MEN1 (0.35) | MEN1KMT2ALMNAGAAMAPK1 | |
| SCHEMBL8479902 | 0.87 | ESR2 (0.30) | — | |
| SCHEMBL8481121 | 0.83 | EDNRA (0.37) | MEN1KMT2AEDNRA | |
| SCHEMBL8477936 | 0.80 | EDNRA (0.33) | EDNRA | |
| SCHEMBL8474733 | 0.75 | — | — | |
| SCHEMBL8479821 | 0.72 | EDNRA (0.35) | MEN1KMT2AGAAEDNRA | |
| SCHEMBL11768569 | 0.68 | MEN1 (0.41) | MEN1KMT2ALMNAGAAMAPK1 | |
| SCHEMBL8476988 | 0.66 | ESR2 (0.32) | — | |
| SCHEMBL11766654 | 0.65 | EDNRA (0.41) | MEN1KMT2ALMNAGAAMAPK1 | |
| SCHEMBL8474729 | 0.63 | EDNRA (0.39) | MAPK1SMN1; SMN2EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |