Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4559547 | 0.86 | POLB (0.56) | POLBCYP1A2CYP2D6OPRD1MEN1 | |
| SCHEMBL4557808 | 0.82 | POLB (0.55) | POLBCYP1A2CYP2D6OPRD1MEN1 | |
| SCHEMBL4558588 | 0.82 | POLB (0.55) | POLBCYP1A2CYP2D6OPRD1MEN1 | |
| SCHEMBL4558787 | 0.78 | POLB (0.51) | POLBCYP1A2CYP2D6OPRD1MEN1 | |
| SCHEMBL4559234 | 0.77 | POLB (0.50) | POLBCYP1A2CYP2D6OPRD1MEN1 | |
| SCHEMBL656655 | 0.72 | POLB (0.97) | POLBCYP1A2CYP2D6MAPTCYP3A4 | |
| Hydrochloric Acid SCHEMBL3851668 | 0.71 | POLB (1.00) | POLBCYP1A2CYP2D6MAPTCYP3A4 | |
| SCHEMBL7504156 | 0.71 | POLB (0.93) | POLBCYP1A2CYP2D6MAPTCYP3A4 | |
| SCHEMBL9158000 | 0.71 | POLB (0.57) | POLBMEN1KMT2AMAPTLMNA | |
| SCHEMBL9157991 | 0.71 | POLB (0.57) | POLBMEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880126-A | 9H-Pyridu ((3,4-b) indole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |