Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827819 | 1.00 | TACR1 (0.80) | TACR1 | |
| Hydrochloric Acid SCHEMBL8477747 | 0.99 | TACR1 (0.79) | TACR1 | |
| Hydrochloric Acid SCHEMBL7827762 | 0.99 | TACR1 (0.79) | TACR1 | |
| SCHEMBL7554993 | 0.90 | TACR1 (0.77) | TACR1 | |
| Hydrochloric Acid SCHEMBL7826763 | 0.90 | TACR1 (0.70) | TACR1 | |
| Hydrochloric Acid SCHEMBL8475421 | 0.90 | TACR1 (0.70) | TACR1 | |
| Hydrochloric Acid SCHEMBL8836208 | 0.89 | TACR1 (0.74) | TACR1 | |
| Hydrochloric Acid SCHEMBL7825649 | 0.89 | TACR1 (0.74) | TACR1 | |
| SCHEMBL8481191 | 0.89 | TACR1 (0.76) | TACR1 | |
| SCHEMBL7822755 | 0.89 | TACR1 (0.76) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883098-A | USED AS TACHYKININ ANTAGONISTS IN THE TREATMENT OF RESPIRATORY DISEASES, OPHTHALMIC DISEASES AND INFLAMMATORY DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| US-5670505-A | TACHYKIKIN ANTAGONIST FOR RESPIRATORY DISEASES, OPHTHALMIC DISEASES AND ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |