Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 3/20 | 0.62 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTR3A | P46098 | 4/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.50 |
| ▸ | HTR3B | O95264 | 3/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10970453 | 0.81 | HRH3 (0.61) | HRH4HRH3ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL28024738 | 0.81 | HSD17B10 (0.51) | ALDH1A1CYP1A2HSD17B10CYP3A4USP2 | |
| SCHEMBL10968278 | 0.81 | USP2 (0.44) | HRH4HRH3ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL2190955 | 0.81 | HRH4 (0.65) | HRH4HRH3ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL29997962 | 0.81 | HRH4 (0.65) | HRH4HRH3ALDH1A1CYP1A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL30619069 | 0.80 | HRH3 (0.59) | HRH4HRH3ALDH1A1CYP1A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL26600764 | 0.80 | HRH3 (0.59) | HRH4HRH3ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL14029975 | 0.79 | HRH4 (0.67) | HRH4HRH3ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL2166051 | 0.77 | HRH4 (1.00) | HRH4HRH3ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL785173 | 0.76 | HRH4 (0.54) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027037-A1 | Cyclic compounds | TANABE SEIYAKU CO., LTD. | 2008-01-31 | — | — | US | disclosed |
| US-7273868-B2 | Pyrazine derivatives | TANABE SEIYAKU CO., LTD. (JP) | 2007-09-25 | — | — | US | disclosed |
| US-7220736-B2 | Pyrimidine compounds | TANABE SEIYAKU CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| EP-1277741-A1 | CYCLIC COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027037-A1 | Cyclic compounds | PDE4A, PDE4B, PDE3B | HRH4 286/4885HRH3 1175/4885ALDH1A1 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.