Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475429 | 0.95 | KDM4E (0.32) | KDM4EMAPK1HIF1ATDP1 | |
| SCHEMBL11130773 | 0.92 | EPHX1 (0.44) | EPHX1ALDH1A1 | |
| SCHEMBL353945 | 0.87 | APP (0.33) | — | |
| SCHEMBL9221394 | 0.87 | TDP1 (0.47) | KDM4EMAPK1HIF1ATDP1EPHX1 | |
| SCHEMBL24031868 | 0.82 | PAOX (0.34) | KDM4EPAOX | |
| SCHEMBL19649555 | 0.73 | DPP4 (0.31) | — | |
| SCHEMBL21880857 | 0.73 | — | — | |
| SCHEMBL5969230 | 0.73 | EPHX1 (0.43) | EPHX1MEN1KMT2A | |
| SCHEMBL1477727 | 0.72 | KDM4E (0.42) | KDM4EMAPK1HIF1ATDP1EPHX1 | |
| SCHEMBL12603930 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5997843-A | TECHNETIUM-99M | AMERSHAM INTERNATIONAL PLC (GB) | 1999-12-07 | — | — | US | disclosed |
| WO-1995004552-A2 | RADIOMETAL COMPLEXES THAT LOCALISE IN HYPOXIC TISSUE | AMERSHAM INTERNATIONAL PLC (GB) | 1995-02-16 | — | — | WO | disclosed |