Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | MIF | P14174 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987076 | 0.84 | MIF (0.66) | CYP2C19HIF1AMIFKMT2AMEN1 | |
| SCHEMBL24020497 | 0.84 | MIF (0.66) | CYP2C19HIF1AMIFKMT2AMEN1 | |
| SCHEMBL9076603 | 0.82 | MIF (0.63) | CYP2C19HIF1AMIFKMT2AMEN1 | |
| SCHEMBL1604043 | 0.81 | CYP2C19 (1.00) | CYP2C19HIF1AMIFKMT2AMEN1 | |
| SCHEMBL17047210 | 0.81 | MIF (0.61) | CYP2C19HIF1AMIFKMT2AMEN1 | |
| SCHEMBL831691 | 0.81 | MIF (0.61) | CYP2C19HIF1AMIFKMT2AMEN1 | |
| SCHEMBL1920886 | 0.81 | MIF (0.61) | CYP2C19HIF1AMIFKMT2AMEN1 | |
| SCHEMBL17324925 | 0.81 | MIF (0.61) | CYP2C19HIF1AMIFKMT2AMEN1 | |
| SCHEMBL503944 | 0.79 | MIF (1.00) | CYP2C19HIF1AMIFKMT2AMEN1 | |
| SCHEMBL11076816 | 0.78 | MIF (0.74) | HIF1AMIFKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922716-A | 5H-indeno 1,2-b!pyrazine-2,3-dione derivatives, their preparation and medicinal products containing them | RHONE-POULENC RORER S.A. (FR) | 1999-07-13 | — | — | US | disclosed |