Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.62 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | DHPS | P49366 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2708169 | 0.87 | BCHE (0.56) | MEN1KMT2APABPC1EIF4HRAB9A | |
| SCHEMBL846525 | 0.86 | MEN1 (0.64) | MEN1KMT2APABPC1EIF4HRAB9A | |
| SCHEMBL846660 | 0.82 | NPC1 (0.56) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL846661 | 0.82 | NPC1 (0.56) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL2707418 | 0.80 | KDM4E (0.45) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL2707298 | 0.78 | KMT2A (0.55) | MEN1KMT2APABPC1EIF4HRAB9A | |
| SCHEMBL846056 | 0.78 | BCHE (0.52) | MEN1KMT2ARAB9ANPC1TP53 | |
| SCHEMBL13762083 | 0.77 | MEN1 (1.00) | MEN1KMT2APABPC1EIF4HRAB9A | |
| SCHEMBL846367 | 0.76 | BCHE (0.48) | MEN1KMT2APABPC1EIF4HL3MBTL1 | |
| SCHEMBL846204 | 0.76 | TRPV1 (0.64) | MEN1KMT2APABPC1EIF4HL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603883-B1 | QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-28 | — | — | EP | disclosed |
| EP-2308848-A1 | Quinoline-derived amide modulators of vanilloid VR1 receptor | Janssen Pharmaceutica NV (BE) | 2011-04-13 | — | — | EP | disclosed |