Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949785 | 0.87 | CCNT1 (0.54) | CCNE2CDK4CCND1CCNE1CDK2 | |
| Enmd-981693 SCHEMBL608128 | 0.86 | CCNE2 (0.69) | CCNE2CDK4CCND1CCNE1CDK2 | |
| Enmd-981693 SCHEMBL29350364 | 0.86 | CCNE2 (0.69) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL6949781 | 0.85 | CCNT1 (0.52) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL7501550 | 0.82 | CCNT1 (0.49) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL6952834 | 0.82 | CCNT1 (0.52) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL6949919 | 0.82 | CCNT1 (0.52) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8162074 | 0.80 | MAPT (0.54) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL6440413 | 0.79 | CCNE2 (0.58) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL668748 | 0.79 | CCNE2 (0.57) | CCNE2CDK4CCND1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988863-B2 | Stable complexes of poorly soluble compounds | HOFFMANN LA ROCHE (CH) | 2009-03-18 | — | — | EP | disclosed |