Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 18/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478697 | 1.00 | ESR1 (0.56) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL8478673 | 0.97 | ESR1 (0.53) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL7107781 | 0.96 | ESR1 (0.60) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| Hydrochloric Acid SCHEMBL7105337 | 0.95 | ESR1 (0.60) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL8582272 | 0.95 | ESR1 (0.58) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL8476695 | 0.92 | GCGR (0.52) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL8476393 | 0.91 | KDM4E (0.56) | ESR1ESR2 | |
| SCHEMBL8473117 | 0.91 | ESR1 (0.62) | ESR1ESR2 | |
| SCHEMBL8476813 | 0.90 | ESR1 (0.63) | ESR1ESR2 | |
| SCHEMBL8472976 | 0.90 | GCGR (0.61) | ESR1ESR2PSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958916-A | FOR INHIBITING BONE LOSS OR BONE RESORPTION | ELI LILLY AND COMPANY (US) | 1999-09-28 | — | — | US | disclosed |