Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480422 | 0.91 | TRPV1 (0.50) | TRPV1CYP3A4KCNE1KCNQ1CFTR | |
| SCHEMBL8482576 | 0.84 | TRPV1 (0.49) | TRPV1CYP3A4 | |
| SCHEMBL8481888 | 0.83 | TRPV1 (0.50) | TRPV1CYP3A4 | |
| SCHEMBL8476611 | 0.82 | TRPV1 (0.49) | TRPV1CYP3A4CTSDBACE1 | |
| SCHEMBL8481518 | 0.82 | TRPV1 (0.43) | TRPV1CYP3A4 | |
| SCHEMBL8476857 | 0.81 | TRPV1 (0.44) | TRPV1CYP3A4CFTR | |
| SCHEMBL8476544 | 0.81 | TRPV1 (0.44) | TRPV1CYP3A4 | |
| SCHEMBL8481389 | 0.81 | TRPV1 (0.44) | TRPV1CYP3A4 | |
| SCHEMBL8476966 | 0.81 | TRPV1 (0.49) | TRPV1CYP3A4 | |
| SCHEMBL8480649 | 0.81 | TRPV1 (0.47) | TRPV1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955607-A | TREATING CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-09-21 | — | — | US | disclosed |