⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28752457 | 0.72 | — | — | |
| SCHEMBL2724301 | 0.65 | — | — | |
| SCHEMBL28188641 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL26646346 | 0.63 | — | — | |
| SCHEMBL29116495 | 0.62 | — | — | |
| SCHEMBL22694158 | 0.62 | — | — | |
| SCHEMBL27524281 | 0.60 | — | — | |
| SCHEMBL21082737 | 0.60 | — | — | |
| SCHEMBL28910329 | 0.60 | — | — | |
| SCHEMBL30164308 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138546-C | Certain 1, 4, 5 -tri- substituted imidazole compounds useful as cytokine | ʷ��˿�������ȳ�ķ����˾ | 2004-02-18 | — | — | CN | disclosed |
| CN-1050126-C | Tri-substituted imidazoles, their preparation and use and pharmaceutical compositions containing them | SMITHKLINE BEECHAM CORP (US) | 2000-03-08 | — | — | CN | disclosed |
| US-5929076-A | Cycloalkyl substituted imidazoles | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| CN-1218801-A | Tri-substituted imidazoles, and process of their preparation and using the same and having their pharmic composition | SMITHKLINE BEECHAM CORP (US) | 1999-06-09 | — | — | CN | disclosed |
| CN-1177959-A | Novel compounds | SMITHKLINE BEECHAM CORP (US) | 1998-04-01 | — | — | CN | disclosed |
| CN-1177299-A | Certain 1, 4, 5 -tri- substituted imidazole compounds useful as cytokine | SMITHKLINE BEECHAM CORP (US) | 1998-03-25 | — | — | CN | disclosed |
| CN-1129447-A | Trisubstituted imidazoles having multiple therapeutic effects | SMITHKLINE BEECHAM CORP (US) | 1996-08-21 | — | — | CN | disclosed |
| CN-1083473-A | New imidazolium compounds and pharmaceutical composition thereof | SMITHKLINE BEECHAM CORP (US) | 1994-03-09 | — | — | CN | disclosed |