Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | ESR1 | P03372 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | PTPN7 | P35236 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 1/20 | 1.00 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477662 | 1.00 | HSD17B10 (1.00) | HSD17B10KDM4ETDP1POLBUSP2 | |
| SCHEMBL2117385 | 1.00 | HSD17B10 (1.00) | HSD17B10KDM4ETDP1POLBUSP2 | |
| SCHEMBL30923529 | 0.88 | HSD17B10 (0.79) | HSD17B10KDM4ETDP1POLBUSP2 | |
| SCHEMBL11021033 | 0.88 | HSD17B10 (0.79) | HSD17B10KDM4ETDP1POLBUSP2 | |
| SCHEMBL11021035 | 0.88 | HSD17B10 (0.79) | HSD17B10KDM4ETDP1POLBUSP2 | |
| SCHEMBL10897219 | 0.88 | HSD17B10 (0.79) | HSD17B10KDM4ETDP1POLBUSP2 | |
| SCHEMBL30923527 | 0.88 | HSD17B10 (0.79) | HSD17B10KDM4ETDP1POLBUSP2 | |
| SCHEMBL30923534 | 0.88 | HSD17B10 (0.79) | HSD17B10KDM4ETDP1POLBUSP2 | |
| SCHEMBL9726349 | 0.85 | HSD17B10 (0.73) | HSD17B10KDM4ETDP1POLBUSP2 | |
| SCHEMBL9206274 | 0.85 | HSD17B10 (0.73) | HSD17B10KDM4ETDP1POLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310904-A | Intermediate | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-10 | — | — | US | claimed |
| EP-0551076-A1 | Process for preparing optically active benzothiazepine compounds by asymmetric reduction | TANABE SEIYAKU CO., LTD. (JP) | 1993-07-14 | — | — | EP | claimed |
| US-5945533-A | Process for preparing optically active benzothiazepine compound and intermediate therefor | TANABE SEIYAKU CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0826678-A1 | Process for preparing optically active benzothiazepine compound, and intermediate therefor | TANABE SEIYAKU CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |
| US-5310904-A | Intermediate | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0551076-A1 | Process for preparing optically active benzothiazepine compounds by asymmetric reduction | TANABE SEIYAKU CO., LTD. (JP) | 1993-07-14 | — | — | EP | disclosed |