Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831328 | 1.00 | TACR1 (0.64) | TACR1KDM4EALDH1A1 | |
| SCHEMBL7827040 | 0.91 | TACR1 (0.71) | TACR1 | |
| SCHEMBL7828222 | 0.91 | TACR1 (0.71) | TACR1 | |
| Hydrochloric Acid SCHEMBL7826462 | 0.90 | TACR1 (0.70) | TACR1 | |
| SCHEMBL7826404 | 0.89 | TACR1 (0.67) | TACR1 | |
| SCHEMBL7561522 | 0.89 | TACR1 (0.67) | TACR1 | |
| SCHEMBL7463674 | 0.88 | TACR1 (0.71) | TACR1 | |
| SCHEMBL7815987 | 0.88 | TACR1 (0.66) | TACR1 | |
| Hydrochloric Acid SCHEMBL8479828 | 0.88 | TACR1 (0.66) | TACR1 | |
| Hydrochloric Acid SCHEMBL7471553 | 0.88 | TACR1 (0.70) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883098-A | USED AS TACHYKININ ANTAGONISTS IN THE TREATMENT OF RESPIRATORY DISEASES, OPHTHALMIC DISEASES AND INFLAMMATORY DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| US-5670505-A | TACHYKIKIN ANTAGONIST FOR RESPIRATORY DISEASES, OPHTHALMIC DISEASES AND ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |