SCHEMBL8478282

SCHEMBL8478282

FC(F)(F)c1[c]ccc2c3ccc(nc3)c12

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
GPR3 P46089 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8481479 0.77
SCHEMBL8482858 0.75
SCHEMBL8477773 0.71 PDPK1 (0.34) KDM4EGPR3
SCHEMBL7450361 0.69 NT5E (0.31)
SCHEMBL12474840 0.65 KDM4E (0.46) KDM4EGPR3
SCHEMBL31684807 0.64 KDM4E (0.59) KDM4EGPR3
SCHEMBL159416 0.64 KDM4E (0.59) KDM4EGPR3
Hydrochloric Acid SCHEMBL9110426 0.62 KDM4E (0.57) KDM4EGPR3
SCHEMBL6067185 0.61 HPRT1 (0.50) KDM4E
SCHEMBL8483317 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5939418-A ANTICOAGULANT THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1999-08-17 US disclosed