Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 3/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 3/20 | 0.38 |
| ▸ | ATP4B | P51164 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1802029 | 0.90 | CDK5 (0.41) | CDK5CDK5R1PDPK1ATP4AATP4B | |
| SCHEMBL1798014 | 0.90 | PTPN11 (0.45) | CDK5CDK5R1PDPK1ATP4AATP4B | |
| SCHEMBL3355063 | 0.88 | CDK5 (0.40) | CDK5CDK5R1PDPK1ATP4AATP4B | |
| SCHEMBL3349790 | 0.87 | PDPK1 (0.41) | CDK5CDK5R1PDPK1ATP4AATP4B | |
| SCHEMBL1798013 | 0.85 | PDPK1 (0.40) | CDK5CDK5R1PDPK1ATP4AATP4B | |
| SCHEMBL12616932 | 0.84 | PDPK1 (0.39) | CDK5CDK5R1PDPK1ATP4AATP4B | |
| SCHEMBL1802952 | 0.84 | PDPK1 (0.38) | CDK5CDK5R1PDPK1ATP4AATP4B | |
| SCHEMBL1798575 | 0.84 | BRD4 (0.39) | CDK5CDK5R1PDPK1ATP4AATP4B | |
| SCHEMBL1801187 | 0.84 | PDPK1 (0.39) | CDK5CDK5R1PDPK1ATP4AATP4B | |
| SCHEMBL1798570 | 0.84 | PDPK1 (0.39) | CDK5CDK5R1PDPK1ATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749829-B1 | JNK inhibitors | EISAI R&D MAN CO LTD (JP) | 2010-11-03 | — | — | EP | disclosed |