Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 19/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038612 | 0.99 | LSS (0.70) | LSS | |
| SCHEMBL5035496 | 0.95 | LSS (0.68) | LSS | |
| SCHEMBL8484967 | 0.93 | LSS (0.66) | LSS | |
| SCHEMBL5038691 | 0.91 | LSS (0.66) | LSS | |
| SCHEMBL5043701 | 0.89 | LSS (0.65) | LSS | |
| SCHEMBL5038777 | 0.89 | LSS (0.65) | LSS | |
| SCHEMBL5043552 | 0.88 | LSS (0.57) | LSS | |
| SCHEMBL5040185 | 0.88 | LSS (0.57) | LSS | |
| SCHEMBL3981917 | 0.87 | LSS (0.71) | LSS | |
| SCHEMBL5043611 | 0.85 | LSS (0.88) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0778271-A2 | Aminoalkyl-substituted benzo-heterocyclic compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |