Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 17/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483828 | 0.89 | LSS (0.44) | LSSMEN1KMT2A | |
| SCHEMBL8483917 | 0.88 | LSS (0.41) | LSSMEN1KMT2A | |
| SCHEMBL8482869 | 0.87 | LSS (0.42) | LSSMEN1KMT2A | |
| Fumaric Acid SCHEMBL8481419 | 0.86 | LSS (0.47) | LSSMEN1KMT2A | |
| SCHEMBL8485026 | 0.86 | LSS (0.39) | LSSMEN1KMT2A | |
| SCHEMBL8481290 | 0.85 | LSS (0.39) | LSSMEN1KMT2APLK1 | |
| SCHEMBL8482097 | 0.71 | — | — | |
| SCHEMBL8478939 | 0.66 | LSS (0.48) | LSSMEN1KMT2A | |
| SCHEMBL8480059 | 0.63 | — | — | |
| SCHEMBL8483920 | 0.62 | LSS (0.51) | LSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |