Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 6/20 | 0.40 |
| ▸ | CBFB | Q13951 | 2/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957125 | 0.84 | MAPK14 (0.58) | PTGESCYP2C9MAPTRAB9AMAPK14 | |
| SCHEMBL8482422 | 0.83 | MAPT (0.42) | MAPTL3MBTL1RAB9AMAPK14MAPK13 | |
| SCHEMBL8480021 | 0.82 | MAPK13 (0.44) | PTGESMAPTRAB9AMAPK14MAPK13 | |
| SCHEMBL8478420 | 0.79 | MAPK14 (0.39) | MAPTL3MBTL1RAB9AMAPK14MAPK13 | |
| SCHEMBL8476402 | 0.78 | MAPK13 (0.47) | MAPTL3MBTL1MAPK14MAPK13MAPK12 | |
| SCHEMBL8791036 | 0.76 | MAPK14 (0.55) | PTGESCYP2C9MAPTRAB9AMAPK14 | |
| SCHEMBL17002178 | 0.76 | MAPK14 (0.63) | CYP2C9MAPTRAB9AMAPK14MAPK13 | |
| SCHEMBL8793341 | 0.76 | MAPK14 (0.63) | CYP2C9MAPTRAB9AMAPK14MAPK13 | |
| SCHEMBL8481639 | 0.75 | MAPK13 (0.44) | L3MBTL1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL8791756 | 0.74 | MAPK14 (0.55) | PTGESCYP2C9MAPTRAB9AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5959113-A | REACTING A DIKETONE DERIVATIVE WITH AN ALDEHYDE DERIVATIVE; ADMINISTERING TO TREAT ATHEROSCLEROSIS, PSORIASIS, ALOPECIA AND TUMORS | HOFFMANN-LA ROCHE INC. (US) | 1999-09-28 | — | — | US | disclosed |