Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15684033 | 0.90 | MEN1 (0.73) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL8480251 | 0.89 | MEN1 (0.76) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL14389682 | 0.88 | MEN1 (0.70) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL16376447 | 0.87 | MEN1 (0.77) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL16376448 | 0.87 | MEN1 (0.77) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL20413823 | 0.87 | MEN1 (0.77) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL28047012 | 0.87 | MEN1 (0.77) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL20220277 | 0.87 | MEN1 (0.77) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL4357711 | 0.87 | MEN1 (0.77) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL12655454 | 0.87 | MEN1 (0.77) | MEN1KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922743-A | USEFUL FOR AMELIORATION OF NERVE DISORDERS DUE TO NEURONAL DEGENERATION, SUCH AS INDUCED BY DRUGS OR ALCOHOL, INFLAMMATORY DISORDERS, DIABETES, ALZHEIMER'S DISEASE, PARKINSON'S DISEASE, HUNTINGTON'S CHOREA, AND OTHERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0795545-A1 | PYRIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1997-09-17 | — | — | EP | disclosed |