Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.80 |
| ▸ | HTR6 | P50406 | 6/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8506913 | 0.81 | SLC6A4 (0.70) | SLC6A4HTR6HTR1AHTR1BHTR2C | |
| SCHEMBL6968677 | 0.81 | SLC6A4 (0.70) | SLC6A4HTR6HTR1AHTR1BHTR2C | |
| SCHEMBL8484999 | 0.80 | SLC6A4 (0.67) | SLC6A4HTR6HTR1ASLC6A3 | |
| SCHEMBL8506286 | 0.80 | SLC6A4 (0.67) | SLC6A4HTR6HTR1AHTR1B | |
| SCHEMBL8507173 | 0.79 | SLC6A4 (0.66) | SLC6A4HTR6HTR1AHTR1B | |
| SCHEMBL8506945 | 0.79 | SLC6A4 (0.66) | SLC6A4HTR6 | |
| SCHEMBL8507360 | 0.79 | SLC6A4 (0.66) | SLC6A4HTR6HTR1B | |
| SCHEMBL6962932 | 0.79 | SLC6A4 (0.66) | SLC6A4HTR6 | |
| SCHEMBL6974695 | 0.78 | SLC6A4 (0.65) | SLC6A4HTR6 | |
| SCHEMBL6969543 | 0.77 | SLC6A4 (0.64) | SLC6A4HTR6HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856510-A | SELECTIVE FOR 5-HT(1D)-LIKE RECEPTORS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1999-01-05 | — | — | US | disclosed |