Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | SI | P14410 | 4/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478203 | 0.93 | MGAM (0.43) | MGAMGAASIMGAM2PDE4A | |
| SCHEMBL8474097 | 0.91 | MGAM (0.41) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL8481462 | 0.91 | MGAM (0.42) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL8479773 | 0.91 | MGAM (0.42) | MGAMGAASIMGAM2HTT | |
| SCHEMBL8479437 | 0.86 | GAA (0.44) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL8478626 | 0.83 | MGAM (0.41) | MGAMGAASIMGAM2PDE4A | |
| SCHEMBL8480711 | 0.83 | MGAM (0.43) | MGAMGAASIMGAM2PDE4A | |
| SCHEMBL8474826 | 0.81 | MGAM (0.41) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL8479017 | 0.81 | MGAM (0.42) | MGAMGAASIMGAM2HTT | |
| SCHEMBL8474730 | 0.80 | PDE4B (0.46) | HTTPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |