Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9176711 | 0.94 | MAPT (0.39) | MAOBARMAPTMAOACASP3 | |
| SCHEMBL20340333 | 0.83 | MAOB (0.39) | MAOBARMAPTMAOACASP3 | |
| SCHEMBL28642287 | 0.75 | MAOB (0.47) | MAOBARMAPTMAOACASP3 | |
| SCHEMBL7008154 | 0.72 | PTPN1 (0.42) | MAOBMAPTKMT2ANPC1RAB9A | |
| SCHEMBL7627864 | 0.71 | MAPT (0.50) | MAOBMAPTMAOACASP3SENP8 | |
| SCHEMBL21527691 | 0.70 | MAOB (0.56) | MAOBMAPTMAOACASP3SENP8 | |
| SCHEMBL21527690 | 0.70 | MAOB (0.56) | MAOBMAPTMAOACASP3SENP8 | |
| SCHEMBL9177550 | 0.68 | MAOB (0.56) | MAOBMAPTMAOACASP3SENP8 | |
| SCHEMBL30382765 | 0.68 | MAOB (0.56) | MAOBMAPTMAOACASP3SENP8 | |
| SCHEMBL30382511 | 0.64 | MAPT (0.45) | MAOBMAPTMAOACYP2C19ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981775-A | FROM A 2'-HYDROXYDEOXYBENZOIN USING PREPARED N,N'-DIMETHYL(CHLOROMETHYLENE)AMMONIUM CHLORIDE AS A REACTANT IN BORONTRIFLUORIDE ETHERATE OR OTHER LEWIS ACID AS A SOLVENT | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1999-11-09 | — | — | US | disclosed |