Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.47 |
| ▸ | FNTB | P49356 | 18/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 9/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481058 | 0.73 | FNTA (0.51) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8481062 | 0.73 | FNTA (0.51) | FNTAFNTBPGGT1BKCNH2 | |
| Hydrochloric Acid SCHEMBL8483237 | 0.72 | FNTA (0.51) | FNTAFNTBPGGT1BKCNH2 | |
| Hydrochloric Acid SCHEMBL8483232 | 0.72 | FNTA (0.51) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7743501 | 0.68 | FNTA (0.54) | FNTAFNTBPGGT1B | |
| SCHEMBL8141157 | 0.68 | FNTA (0.72) | FNTAFNTBPGGT1B | |
| SCHEMBL7743768 | 0.67 | FNTA (0.66) | FNTAFNTBPGGT1B | |
| SCHEMBL7744106 | 0.67 | FNTA (0.60) | FNTAFNTBPGGT1BKCNH2 | |
| Hydrochloric Acid SCHEMBL7746020 | 0.66 | FNTA (0.59) | FNTAFNTBPGGT1BKCNH2 | |
| Hydrochloric Acid SCHEMBL7738189 | 0.66 | FNTA (0.64) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977134-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-11-02 | — | — | US | disclosed |