Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 5/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2753819 | 0.90 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CGPIK3CBHTR6 | |
| SCHEMBL8446932 | 0.90 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CGPIK3CBHTR6 | |
| SCHEMBL3347277 | 0.88 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CGPIK3CBHTR6 | |
| SCHEMBL3355006 | 0.88 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CGPIK3CBHTR6 | |
| SCHEMBL2752171 | 0.86 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CGPIK3CBHTR6 | |
| SCHEMBL8177899 | 0.85 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3CGPIK3CBHTR6 | |
| SCHEMBL2753130 | 0.84 | PIK3CA (0.48) | PIK3CDPIK3CAPIK3CGPIK3CBHTR6 | |
| SCHEMBL2753364 | 0.84 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CGPIK3CBHTR6 | |
| SCHEMBL2752645 | 0.83 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CGPIK3CBHTR6 | |
| SCHEMBL2753448 | 0.83 | MAPK8 (0.46) | PIK3CDPIK3CAPIK3CGPIK3CBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749829-B1 | JNK inhibitors | EISAI R&D MAN CO LTD (JP) | 2010-11-03 | — | — | EP | disclosed |