Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23453516 | 0.83 | TP53 (0.59) | HTTTP53FOLH1ALDH1A1ALOX15 | |
| SCHEMBL623624 | 0.82 | TP53 (0.57) | HTTTP53FOLH1ALDH1A1ALOX15 | |
| SCHEMBL3098697 | 0.80 | TP53 (0.60) | HTTTP53FOLH1ALDH1A1ALOX15 | |
| SCHEMBL1521052 | 0.80 | TP53 (0.56) | HTTTP53FOLH1ALDH1A1ALOX15 | |
| SCHEMBL31617745 | 0.80 | HTT (0.56) | HTTTP53FOLH1ALDH1A1ALOX15 | |
| SCHEMBL534811 | 0.80 | HTT (0.56) | HTTTP53FOLH1ALDH1A1ALOX15 | |
| SCHEMBL28980885 | 0.80 | TP53 (0.56) | HTTTP53FOLH1ALDH1A1ALOX15 | |
| SCHEMBL1368181 | 0.78 | TP53 (0.63) | HTTTP53FOLH1ALDH1A1ALOX15 | |
| SCHEMBL722641 | 0.77 | HTT (0.53) | HTTTP53FOLH1ALDH1A1ALOX15 | |
| SCHEMBL12164265 | 0.77 | KDM4E (0.55) | HTTTP53FOLH1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856334-A | ANTAGONIST FOR EOSINOPHILS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0773219-A1 | IMIDAZOQUINOLINE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |