Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 18/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483920 | 0.89 | LSS (0.51) | LSSMEN1KMT2ATHRATHRB | |
| SCHEMBL8483830 | 0.87 | LSS (0.49) | LSSMEN1KMT2ATHRATHRB | |
| SCHEMBL8478939 | 0.87 | LSS (0.48) | LSSMEN1KMT2ATHRATHRB | |
| SCHEMBL8485033 | 0.85 | LSS (0.49) | LSSMEN1KMT2ATHRATHRB | |
| SCHEMBL8481295 | 0.79 | LSS (0.46) | LSSMEN1KMT2A | |
| SCHEMBL8479424 | 0.77 | LSS (0.49) | LSSMEN1KMT2ATHRATHRB | |
| SCHEMBL3679175 | 0.72 | LSS (0.72) | LSSMEN1KMT2A | |
| SCHEMBL8045882 | 0.69 | LSS (0.74) | LSSMEN1KMT2A | |
| SCHEMBL8484290 | 0.69 | LSS (0.48) | LSSMEN1KMT2A | |
| SCHEMBL7681945 | 0.69 | LSS (0.76) | LSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |