Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 6/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.41 |
| ▸ | NPY1R | P25929 | 5/20 | 0.41 |
| ▸ | NPY2R | P49146 | 3/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | TFPI | P10646 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620200 | 0.94 | HDAC4 (0.45) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL11225353 | 0.87 | NPY4R (0.41) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL1925288 | 0.87 | NPY4R (0.41) | NPY4RNPY5RNPY1RNPY2RTFPI | |
| SCHEMBL11132931 | 0.84 | NPY4R (0.39) | NPY4RNPY5RNPY1RNPY2RTFPI | |
| Hydrochloric Acid SCHEMBL11482111 | 0.84 | CA12 (0.45) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL9490193 | 0.82 | SIRT2 (0.48) | SIRT5HDAC1 | |
| SCHEMBL8341786 | 0.81 | HDAC1 (0.43) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL3396260 | 0.80 | AAK1 (0.44) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL27439945 | 0.80 | AAK1 (0.44) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL29405051 | 0.78 | CA12 (0.49) | NPY4RNPY5RNPY1RNPY2RSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554314-B1 | A METHOD OF DETERMINING PORPHYROMONAS GINGIVALIS | WIKSTROEM MAUDE BIRGITTA (SE) | 1996-08-14 | — | — | EP | claimed |
| US-5981164-A | RAPID AND SIMPLE DIAGNOSIS OF PERIODONTITIS BY REACTING SAMPLE WITH SUBSTRATE FOR TRYPSIN-LIKE AMIDASE, A MARKER SYSTEM, AND A MONO- OR DIPEPTIDE ENHANCER CONTAINING GLYCINE DERIVATIVE; ANALYZING MIXTURE FOR SIGNAL GENERATED BY MARKER | WIKSTROEM MAUDE BIRGITTA (SE) | 1999-11-09 | — | — | US | disclosed |
| EP-0554314-B1 | A METHOD OF DETERMINING PORPHYROMONAS GINGIVALIS | WIKSTROEM MAUDE BIRGITTA (SE) | 1996-08-14 | — | — | EP | disclosed |
| EP-0255341-B1 | REAGENT FOR TESTING PERIODONTAL DISEASES | SUNSTAR KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |
| EP-0255341-A2 | Reagent for testing periodontal diseases | SUNSTAR KABUSHIKI KAISHA (JP) | 1988-02-03 | — | — | EP | disclosed |