Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 7/20 | 0.70 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA7 | P43166 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760809 | 0.82 | LSS (1.00) | LSS | |
| SCHEMBL6716346 | 0.79 | CA1 (0.69) | LSSCA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL6718966 | 0.78 | CA1 (0.67) | LSSCA1CA2CA7CA9 | |
| SCHEMBL8483502 | 0.75 | LSS (0.61) | LSSCA1CA2CA7CA9 | |
| SCHEMBL8759892 | 0.74 | LSS (0.61) | LSSMAOBMAOA | |
| SCHEMBL8482365 | 0.73 | LSS (0.73) | LSSCA1CA2CA7CA9 | |
| SCHEMBL8483497 | 0.73 | LSS (0.52) | LSSCA1CA2CA7CA9 | |
| SCHEMBL8482367 | 0.73 | LSS (0.73) | LSSCA1CA2CA7CA9 | |
| SCHEMBL8485500 | 0.72 | LSS (0.61) | LSSMAOBMAOA | |
| SCHEMBL8483929 | 0.72 | LSS (0.58) | LSSCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0778271-A2 | Aminoalkyl-substituted benzo-heterocyclic compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |