Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 6/20 | 0.60 |
| ▸ | TACR1 | P25103 | 4/20 | 0.60 |
| ▸ | TACR3 | P29371 | 7/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482751 | 0.87 | TACR2 (0.67) | TACR2TACR1TACR3CCR5 | |
| SCHEMBL8482847 | 0.85 | TACR2 (0.66) | TACR2TACR1TACR3CCR5 | |
| SCHEMBL6950402 | 0.84 | TACR1 (0.61) | TACR2TACR1TACR3 | |
| SCHEMBL7870009 | 0.82 | TACR2 (0.73) | TACR2TACR1TACR3 | |
| SCHEMBL14089179 | 0.81 | TACR2 (0.75) | TACR2TACR1TACR3 | |
| SCHEMBL6952599 | 0.80 | TACR2 (0.73) | TACR2TACR1TACR3 | |
| SCHEMBL7864418 | 0.80 | TACR2 (0.65) | TACR2TACR1TACR3CCR5 | |
| SCHEMBL7312636 | 0.79 | TACR2 (0.66) | TACR2TACR1TACR3 | |
| Hydrochloric Acid SCHEMBL7751882 | 0.78 | TACR2 (0.65) | TACR2TACR1TACR3 | |
| SCHEMBL8478954 | 0.78 | TACR2 (0.72) | TACR2TACR1TACR3CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008223-A | ANTIINFLAMMATORY AGENTS FOR TREATING ASTHMA | ZENECA LIMITED (GB) | 1999-12-28 | — | — | US | disclosed |
| US-5731309-A | Substituted heteroalkyleneamine neurokinin antagonists | ZENECA LIMITED (GB) | 1998-03-24 | — | — | US | disclosed |