N-Acetylaspartic Acid

N-Acetylaspartic Acid

SCHEMBL848463

CC(=O)N[C@H](CC(=O)O)C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.61
KDM4E B2RXH2 1/20 0.61
THRB P10828 1/20 0.61
ALOX15 P16050 1/20 0.61
NFKB1 P19838 1/20 0.61
PTGS2 P35354 1/20 0.61
THPO P40225 1/20 0.61
RECQL P46063 1/20 0.61
BLM P54132 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
ALDH1A1 P00352 1/20 0.59
GNPAT O15228 1/20 0.57
CA2 P00918 3/20 0.52
CA4 P22748 1/20 0.52
FNTA P49354 2/20 0.46
FNTB P49356 2/20 0.46
MME P08473 4/20 0.44
GAA P10253 1/20 0.42
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Acetylaspartic Acid SCHEMBL31119891 1.00 MAPT (0.61) MAPTKDM4ETHRBALOX15NFKB1
N-Acetylaspartic Acid SCHEMBL37946 1.00 MAPT (0.61) MAPTKDM4ETHRBALOX15NFKB1
N-Acetylaspartic Acid SCHEMBL163861 1.00 MAPT (0.61) MAPTKDM4ETHRBALOX15NFKB1
N-Acetylaspartic Acid SCHEMBL28602698 0.98 MAPT (0.59) MAPTKDM4ETHRBALOX15NFKB1
N-Acetylaspartic Acid SCHEMBL27883016 0.98 MAPT (0.59) MAPTKDM4ETHRBALOX15NFKB1
N-Acetylaspartic Acid SCHEMBL27980402 0.98 MAPT (0.59) MAPTKDM4ETHRBALOX15NFKB1
N-Acetylaspartic Acid SCHEMBL27980404 0.98 MAPT (0.59) MAPTKDM4ETHRBALOX15NFKB1
N-Acetylaspartic Acid SCHEMBL27908998 0.98 MAPT (0.59) MAPTKDM4ETHRBALOX15NFKB1
N-Acetylaspartic Acid SCHEMBL28715832 0.98 MAPT (0.59) MAPTKDM4ETHRBALOX15NFKB1
N-Acetylaspartic Acid SCHEMBL27908423 0.98 MAPT (0.59) MAPTKDM4ETHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102066314-B Process of preparation of optically active alpha aminoacetals CLARIANT SPECIALTY FINE CHEM 2014-07-30 CN claimed
CN-1434795-B Acylated Pseudodipeptides with Functionalized Auxiliary Branches OM PHARMA 2012-11-14 CN claimed
EP-2183201-B1 PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS ESTEVE QUIMICA SA (ES) 2012-03-28 EP claimed
US-7968712-B2 Process for the resolution of zopiclone and intermediate compounds ESTEVE QUIMICA, S.A. (ES) 2011-06-28 US claimed
CN-102066314-A Process of preparation of optically active alpha aminoacetals CLARIANT SPECIALTY FINE CHEM 2011-05-18 CN claimed
US-20100274018-A1 PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS ESTEVE QUIMICA, S.A. (ES) 2010-10-28 US claimed
US-7772396-B2 Process for the resolution of zopiclone and intermediate compounds Esteve Quimica, S.A. Avda. Mare de deu de Monsterrat (ES) 2010-08-10 US claimed
CN-101772475-A Method and intermediate compounds for resolving zopiclone ESTEVE QUIMICA SA 2010-07-07 CN claimed
EP-2183201-A1 PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS Esteve Química, S.A. (ES) 2010-05-12 EP claimed
WO-2009016251-A1 PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS Esteve Química, S.A. (ES) 2009-02-05 WO claimed
US-20090036681-A1 PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS ESTEVE QUIMICA, S.A. (ES) 2009-02-05 US claimed
EP-2020403-A1 Process for the resolution of zopiclone and intermediate compounds ESTEVE QUIMICA, S.A. (ES) 2009-02-04 EP claimed
CN-1874992-A Resolution of 3-amino alkylnitriles PFIZER (US) 2006-12-06 CN claimed
WO-2025006958-A2 METHODS OF TREATING AMYLOIDOSIS OF THE SKIN AND REJUVENATING SKIN USING BIOSENSORS RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2025-01-02 WO disclosed
CN-118369325-A Therapeutic compounds for HIV virus infection 吉利德科学公司 2024-07-19 CN disclosed
US-20240132558-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS INC (US) 2024-04-25 US disclosed
WO-2009016251-A1 PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS Esteve Química, S.A. (ES) 2009-02-05 WO disclosed
US-20090036681-A1 PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS ESTEVE QUIMICA, S.A. (ES) 2009-02-05 US disclosed
EP-2020403-A1 Process for the resolution of zopiclone and intermediate compounds ESTEVE QUIMICA, S.A. (ES) 2009-02-04 EP disclosed
CN-1874992-A Resolution of 3-amino alkylnitriles PFIZER (US) 2006-12-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100274018-A1 PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS CYP3A5, ZP1, AZI2 MAPT 2951/4885KDM4E 1637/4885THRB 3477/4885
US-20240132558-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, VIP MAPT 2759/4885KDM4E 4705/4885THRB 1875/4885
US-20090036681-A1 PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS CYP3A5, ZP1, AZI2 MAPT 2951/4885KDM4E 1637/4885THRB 3477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.