Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.34 |
| ▸ | FNTB | P49356 | 6/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485039 | 0.91 | FNTA (0.42) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8492476 | 0.83 | FNTA (0.40) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8501338 | 0.83 | FNTA (0.37) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL8497694 | 0.83 | NR2E1 (0.32) | FNTAFNTBPGGT1BKMT2AMEN1 | |
| SCHEMBL8503537 | 0.82 | MAPT (0.35) | FNTAFNTBPGGT1BKMT2AMEN1 | |
| SCHEMBL8610253 | 0.81 | FNTA (0.42) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8498811 | 0.80 | FNTA (0.39) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8495276 | 0.78 | FNTA (0.42) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8494113 | 0.77 | CYP11B1 (0.42) | FNTAFNTBPGGT1B | |
| SCHEMBL8497638 | 0.77 | FNTA (0.40) | FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999012912-A1 | THIOUREA DERIVATIVES OR NON-TOXIC SALTS THEREOF FOR INHIBITNG RAS-TRANSFORMED CELL GROWTH | YUHAN CORPORATION (KR) | 1999-03-18 | — | — | WO | disclosed |