SCHEMBL8485486

SCHEMBL8485486

O=C(NCP(=O)(O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.59
EPHX2 P34913 1/20 0.53
FABP7 O15540 2/20 0.46
FABP5 Q01469 2/20 0.46
MDM4 O15151 1/20 0.45
TP53 P04637 1/20 0.45
CASP3 P42574 2/20 0.45
PIN1 Q13526 1/20 0.42
OPRD1 P41143 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30761547 1.00 KMT2A (0.59) KMT2AEPHX2FABP7FABP5MDM4
SCHEMBL422645 0.87 KMT2A (0.62) KMT2AEPHX2FABP7FABP5MDM4
Phosphoric Acid SCHEMBL22468200 0.83 KMT2A (0.60) KMT2AEPHX2FABP7FABP5MDM4
SCHEMBL30697177 0.83 KMT2A (0.63) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL16140731 0.83 KMT2A (0.63) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL30987806 0.82 KMT2A (0.59) KMT2AEPHX2FABP7FABP5MDM4
SCHEMBL17143722 0.82 KMT2A (0.59) KMT2AEPHX2FABP7FABP5MDM4
SCHEMBL29359416 0.82 KMT2A (0.59) KMT2AEPHX2FABP7FABP5MDM4
SCHEMBL29468722 0.82 KMT2A (0.66) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL3171101 0.82 KMT2A (0.66) KMT2AEPHX2FABP7FABP5CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113249112-B Quantum dot and application thereof 东友精细化工有限公司 2025-02-07 CN disclosed
CN-113248953-B Photoconversion curable composition, cured film, quantum dot light-emitting diode, and image display device 东友精细化工有限公司 2023-02-21 CN disclosed
CN-113248953-A Photoconversion curable composition, cured film, quantum dot light-emitting diode, and image display device 东友精细化工有限公司 2021-08-13 CN disclosed
CN-113249112-A Quantum dots and applications thereof 东友精细化工有限公司 2021-08-13 CN disclosed
US-5883255-A Substituted indolizino 1,2-b!quinolinones SMITHKLINE BEECHAM CORPORATION (US) 1999-03-16 US disclosed
EP-0637960-A4 SUBSTITUTED INDOLIZINO 1,2-b]QUINOLINONES. SMITHKLINE BEECHAM CORP (US) 1995-06-07 EP disclosed
EP-0637960-A1 SUBSTITUTED INDOLIZINO 1,2-b]QUINOLINONES SMITHKLINE BEECHAM CORPORATION (US) 1995-02-15 EP disclosed
CN-1083064-A Indolizino [1, the 2-b] quinolinones that replaces SMITHKLINE BEECHAM CORP (US) 1994-03-02 CN disclosed
WO-1993020818-A1 SUBSTITUTED INDOLIZINO[1,2-b]QUINOLINONES SMITHKLINE BEECHAM CORPORATION (US) 1993-10-28 WO disclosed