Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816767 | 0.83 | TDP1 (0.66) | TDP1SIRT3CYP2A6BAZ2BALDH1A1 | |
| SCHEMBL1024936 | 0.81 | TDP1 (0.42) | TDP1SIRT3CYP2A6ALDH1A1MAPT | |
| SCHEMBL36668757 | 0.79 | TDP1 (0.71) | TDP1SIRT3ALDH1A1MAPTKDM4E | |
| SCHEMBL286483 | 0.79 | TDP1 (0.71) | TDP1SIRT3ALDH1A1MAPTKDM4E | |
| SCHEMBL8226949 | 0.79 | TDP1 (0.50) | TDP1SIRT3CYP2A6ALDH1A1MAPT | |
| SCHEMBL11001665 | 0.79 | TDP1 (0.50) | TDP1SIRT3CYP2A6ALDH1A1MAPT | |
| SCHEMBL2470189 | 0.76 | TDP1 (0.47) | TDP1SIRT3CYP2A6ALDH1A1MAPT | |
| SCHEMBL1877896 | 0.76 | TDP1 (0.47) | TDP1SIRT3CYP2A6ALDH1A1MAPT | |
| SCHEMBL11341427 | 0.75 | CYP2A6 (0.47) | TDP1SIRT3CYP2A6BAZ2BALDH1A1 | |
| SCHEMBL30990565 | 0.75 | CYP2A6 (0.44) | TDP1SIRT3CYP2A6BAZ2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |