Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.69 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP9 | P55211 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778581 | 0.92 | PTGIR (0.81) | PTGIRPTGDRPTGER1PTGER3ABCB1 | |
| SCHEMBL7778649 | 0.84 | PTGIR (0.66) | PTGIRPTGDRPTGER1PTGER3ABCB1 | |
| SCHEMBL7772426 | 0.83 | PTGIR (0.54) | PTGIRPTGDRPTGER1PTGER3ABCB1 | |
| SCHEMBL8485899 | 0.83 | PTGIR (0.67) | PTGIRPTGDRPTGER1PTGER3ABCB1 | |
| SCHEMBL8486134 | 0.83 | PTGIR (0.57) | PTGIRPTGDRPTGER1PTGER3ABCB1 | |
| SCHEMBL7779787 | 0.82 | PTGIR (1.00) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7778658 | 0.80 | PTGIR (0.49) | PTGIRPTGDRPTGER1PTGER3ABCB1 | |
| SCHEMBL8484992 | 0.80 | PTGIR (0.58) | PTGIRPTGDRPTGER1PTGER3ABCB1 | |
| SCHEMBL7778653 | 0.80 | PTGIR (0.49) | PTGIRPTGDRPTGER1PTGER3ABCB1 | |
| SCHEMBL7776642 | 0.80 | PTGIR (0.49) | PTGIRPTGDRPTGER1PTGER3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863918-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |