Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190320 | 1.00 | TACR1 (0.65) | TACR1 | |
| SCHEMBL9016095 | 0.86 | TACR1 (0.74) | TACR1 | |
| SCHEMBL14627507 | 0.86 | TACR1 (0.74) | TACR1 | |
| SCHEMBL7433288 | 0.86 | TACR1 (0.74) | TACR1 | |
| SCHEMBL8200372 | 0.83 | TACR1 (0.57) | TACR1 | |
| SCHEMBL8200385 | 0.79 | TACR1 (0.65) | TACR1 | |
| SCHEMBL8893860 | 0.78 | TACR1 (0.58) | TACR1 | |
| SCHEMBL8893856 | 0.78 | TACR1 (0.58) | TACR1 | |
| SCHEMBL8189477 | 0.77 | TACR1 (0.88) | TACR1 | |
| SCHEMBL8189473 | 0.77 | TACR1 (0.88) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981755-A | Tachykinin antagonists | WARNER-LAMBERT COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| US-5856354-A | RESPIRATORY SYSTEM DISORDERS, ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL DISORDERS, VISION DEFECTS, ANTIALLERGENS,PAIN, NERVOUS SYSTEM DISORDERS, HEADACHES | WARNER-LAMBERT COMPANY (US) | 1999-01-05 | — | — | US | disclosed |
| US-5716979-A | NONPEPTIDES, UNIQUE IN ALKYLATION/SUBSTITUTION PATTERN ALONG THEIR BACKBONE, USEFUL FOR TREATING DISORDERS SUCH AS RESPIRATORY, INFLAMMATORY, GASTROINTESTINAL, OPHTHALMIC, ALLERGIES, PAIN, VASCULAR, MIGRANE, ARTHRITIS AND BRAIN | WARNER-LAMBERT COMPANY (US) | 1998-02-10 | — | — | US | disclosed |
| US-5594022-A | CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0655055-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |