SCHEMBL848686

SCHEMBL848686

O=C1c2c([N+](=O)[O-])ccc(O)c2C(=O)c2c(O)c(Br)cc([N+](=O)[O-])c21

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.71
CYP3A4 P08684 3/20 0.71
TP53 P04637 3/20 0.71
HPGD P15428 3/20 0.71
HIF1A Q16665 2/20 0.71
SMN1; SMN2 Q16637 2/20 0.71
MAPT P10636 2/20 0.57
APEX1 P27695 2/20 0.57
POLB P06746 1/20 0.57
CASP6 P55212 1/20 0.57
CSNK2A2 P19784 2/20 0.57
CSNK2B P67870 2/20 0.57
CSNK2A1 P68400 2/20 0.57
CSNK2A3 Q8NEV1 2/20 0.57
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CA12 O43570 4/20 0.43
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11753725 1.00 TSHR (0.71) TSHRCYP3A4TP53HPGDHIF1A
SCHEMBL28592683 0.89 HPGD (0.50) TSHRCYP3A4TP53HPGDHIF1A
SCHEMBL30195179 0.89 HPGD (0.50) TSHRCYP3A4TP53HPGDHIF1A
SCHEMBL849411 0.89 HPGD (0.50) TSHRCYP3A4TP53HPGDHIF1A
SCHEMBL186885 0.84 TSHR (1.00) TSHRCYP3A4TP53HPGDHIF1A
SCHEMBL11648667 0.84 TSHR (1.00) TSHRCYP3A4TP53HPGDHIF1A
SCHEMBL10356144 0.84 TSHR (1.00) TSHRCYP3A4TP53HPGDHIF1A
SCHEMBL10356103 0.84 TSHR (1.00) TSHRCYP3A4TP53HPGDHIF1A
SCHEMBL3501895 0.84 TSHR (1.00) TSHRCYP3A4TP53HPGDHIF1A
SCHEMBL11295880 0.82 TSHR (0.71) TSHRCYP3A4TP53HPGDHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142520-B2 Blue anthraquinone dyes, production and use thereof DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2012-03-27 US disclosed
US-8142520-B2 Blue anthraquinone dyes, production and use thereof DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2012-03-27 US disclosed
US-20100064452-A1 BLUE ANTHRAQUINONE DYES, PRODUCTION AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2010-03-18 US disclosed
US-20100064452-A1 BLUE ANTHRAQUINONE DYES, PRODUCTION AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2010-03-18 US disclosed
WO-2008025733-A1 BLUE ANTHRAQUINONE DYES, PRODUCTION AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 2008-03-06 WO disclosed