Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 6/20 | 0.44 |
| ▸ | MGLL | Q99685 | 4/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL848986 | 0.94 | PTH1R (0.44) | PTH1RMGLLSLC6A7ABL1SCN9A | |
| SCHEMBL848985 | 0.94 | PTH1R (0.44) | PTH1RMGLLSLC6A7ABL1SCN9A | |
| SCHEMBL850216 | 0.94 | PTH1R (0.47) | PTH1RMGLLSLC6A7ABL1SCN9A | |
| SCHEMBL850215 | 0.94 | PTH1R (0.47) | PTH1RMGLLSLC6A7ABL1SCN9A | |
| SCHEMBL13552171 | 0.93 | PTH1R (0.44) | PTH1RMGLLSLC6A7ABL1SCN9A | |
| SCHEMBL849317 | 0.92 | PTH1R (0.44) | PTH1RMGLLSLC6A7ABL1SCN9A | |
| SCHEMBL849318 | 0.92 | PTH1R (0.44) | PTH1RMGLLSLC6A7ABL1SCN9A | |
| SCHEMBL851793 | 0.92 | PTH1R (0.46) | PTH1RMGLLSLC6A7ABL1SCN9A | |
| SCHEMBL851792 | 0.92 | PTH1R (0.46) | PTH1RMGLLSLC6A7ABL1SCN9A | |
| Hydrochloric Acid SCHEMBL848545 | 0.92 | PTH1R (0.44) | PTH1RMGLLSLC6A7ABL1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-B9 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2015-10-28 | — | — | EP | disclosed |
| EP-2433940-B1 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2014-09-24 | — | — | EP | disclosed |
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |