SCHEMBL8487308

SCHEMBL8487308

C=CC(=O)N1CC[C@H](O)[C@H]1C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.35
TEAD1 P28347 1/20 0.33
TEAD3 Q99594 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6475878 1.00 SRC (0.35) SRCTEAD1TEAD3
SCHEMBL30482484 0.85 SRC (0.33) SRC
SCHEMBL11353713 0.78 ACE (0.37)
SCHEMBL11353710 0.78 ACE (0.37)
SCHEMBL11353715 0.78 ACE (0.37)
SCHEMBL1934100 0.77
SCHEMBL2853164 0.77
SCHEMBL20680100 0.77
SCHEMBL22208124 0.77
SCHEMBL5092375 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5858296-A A BIOLOGICALLY ACTIVE MOLECULE FORMED BY POLYMERIZATION OF FUNCTIONAL MONOMERS AROUND A TEMPLATE MOLECULE THAT EXHIBITS DRUG ACTIVITY, REMOVAL OF TEMPLATE AND POLYMERIZATION OF SECOND CLASS OF MONOMER IN THE VOIDS LEFT BY TEMPLATE YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1999-01-12 US disclosed
WO-1996040822-A1 PREPARATION OF BIOLOGICALLY ACTIVE MOLECULES BY MOLECULAR IMPRINTING YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (US) 1996-12-19 WO disclosed