Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767538 | 1.00 | KDM4E (0.38) | KDM4ECHRM4IRAK4EGFRCYP3A4 | |
| SCHEMBL8767636 | 0.99 | KDM4E (0.39) | KDM4ECHRM4IRAK4EGFRCYP3A4 | |
| SCHEMBL8485348 | 0.99 | KDM4E (0.39) | KDM4ECHRM4IRAK4EGFRCYP3A4 | |
| SCHEMBL8485612 | 0.94 | KDM4E (0.38) | KDM4ECHRM4IRAK4CYP3A4CYP2C9 | |
| SCHEMBL8767585 | 0.94 | KDM4E (0.38) | KDM4ECHRM4IRAK4CYP3A4CYP2C9 | |
| SCHEMBL8486654 | 0.86 | KDM4E (0.38) | KDM4EIRAK4EGFRCYP3A4LMNA | |
| SCHEMBL8767783 | 0.84 | KDM4E (0.39) | KDM4EIRAK4EGFRCYP3A4PKM | |
| SCHEMBL8488831 | 0.84 | KDM4E (0.39) | KDM4EIRAK4EGFRCYP3A4PKM | |
| SCHEMBL8483242 | 0.79 | KDM4E (0.38) | KDM4EIRAK4MEN1 | |
| SCHEMBL8767928 | 0.79 | KDM4E (0.38) | KDM4EIRAK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889012-A | INSECTICIDE, ACARICIDES, FUNGICIDES | HOECHST-SCHERING AGREVO GMBH (DE) | 1999-03-30 | — | — | US | disclosed |