⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14303471 | 1.00 | — | — | |
| SCHEMBL17286038 | 1.00 | — | — | |
| SCHEMBL14444141 | 1.00 | — | — | |
| SCHEMBL20103871 | 1.00 | — | — | |
| SCHEMBL14444139 | 1.00 | — | — | |
| SCHEMBL18070254 | 1.00 | — | — | |
| SCHEMBL24398116 | 0.95 | EPHX1 (0.38) | — | |
| SCHEMBL17031971 | 0.95 | PDGFRB (0.33) | — | |
| SCHEMBL21211597 | 0.95 | EPHX1 (0.35) | — | |
| SCHEMBL19976043 | 0.95 | EPHX1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623799-A | A kind of preparation method of makrolon | 华中科技大学 | 2018-10-09 | — | — | CN | claimed |
| US-20230365561-A1 | BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2023-11-16 | — | — | US | disclosed |
| EP-3661921-B1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NODTHERA LTD (GB) | 2023-10-18 | — | — | EP | disclosed |
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |
| WO-2023066350-A1 | CRBN E3 LIGASE LIGAND COMPOUND, PROTEIN DEGRADING AGENT DEVELOPED ON THE BASIS OF LIGAND COMPOUND, AND THEIR APPLICATIONS | 标新生物医药科技(上海)有限公司 | 2023-04-27 | — | — | WO | disclosed |
| US-20230000813-A1 | COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE | INTERVET INC. (US) | 2023-01-05 | — | — | US | disclosed |
| WO-2022262854-A1 | CLY SERIES COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN PREPARATION OF DRUGS | 南京韦尔优众医药有限公司 | 2022-12-22 | — | — | WO | disclosed |
| WO-2022159421-A1 | IONIZABLE LIPIDS FOR NANOMATERIALS | BEAM THERAPEUTICS INC. (US) | 2022-07-28 | — | — | WO | disclosed |
| CN-105820560-B | Molded article comprising polyamide resin composition | 旭化成株式会社 | 2021-12-03 | — | — | CN | disclosed |
| US-11180578-B2 | Polymerization inhibitor and retarder compositions with amine stabilizer | ECOLAB USA INC. (US) | 2021-11-23 | — | — | US | disclosed |
| EP-1087970-B1 | PYRROLO 2,3-d]PYRIMIDINE COMPOUNDS | PFIZER PROD INC (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2004024728-A2 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-03-25 | — | — | WO | disclosed |
| US-20030212273-A1 | Pyrrolo [2,3-D] pyrimidine compounds | PFIZER INC. | 2003-11-13 | — | — | US | disclosed |
| US-6610847-B2 | Tyrosine kinase inhibitors; immunosuppressants | PFIZER INC. | 2003-08-26 | — | — | US | disclosed |
| CN-1419578-A | Block copolymer | ASAHI CHEMICAL IND (JP) | 2003-05-21 | — | — | CN | disclosed |
| CN-1379666-A | Non-peptide GnRH agents, methods and intermediates for their preparation | AGOURON PHARMA (US) | 2002-11-13 | — | — | CN | disclosed |
| US-20020019526-A1 | Pyrrolo[2,3-d]pyrimidine compounds | PFIZER INC. | 2002-02-14 | — | — | US | disclosed |
| EP-1087970-A1 | PYRROLO 2,3-d]PYRIMIDINE COMPOUNDS | Pfizer Products Inc. (US) | 2001-04-04 | — | — | EP | disclosed |
| CN-1275148-A | Polyamide resin composition and process for producing the same | ASAHI CHEMICAL IND (JP) | 2000-11-29 | — | — | CN | disclosed |
| WO-1999065908-A1 | PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 1999-12-23 | — | — | WO | disclosed |