Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484154 | 0.87 | GRM5 (0.48) | NOTUML3MBTL1NPC1RAB9AHTT | |
| SCHEMBL7810523 | 0.76 | NOTUM (0.72) | NOTUML3MBTL1NPC1RAB9AHTT | |
| SCHEMBL19810876 | 0.76 | NOTUM (0.72) | NOTUML3MBTL1NPC1RAB9AHTT | |
| SCHEMBL23451512 | 0.74 | NOTUM (1.00) | NOTUML3MBTL1NPC1RAB9AHTT | |
| SCHEMBL19627022 | 0.74 | NOTUM (0.70) | NOTUML3MBTL1NPC1RAB9AHTT | |
| SCHEMBL8288457 | 0.74 | NOTUM (0.70) | NOTUML3MBTL1NPC1RAB9AHTT | |
| SCHEMBL11621292 | 0.73 | IDO1 (0.65) | HTTSMN1; SMN2MAPK1CYP1A2CYP2C19 | |
| SCHEMBL30792125 | 0.72 | NOTUM (0.61) | NOTUML3MBTL1NPC1RAB9AHTT | |
| SCHEMBL19555887 | 0.71 | NR1H4 (0.59) | NOTUML3MBTL1NPC1RAB9AHTT | |
| SCHEMBL28923368 | 0.70 | NOTUM (0.57) | NOTUML3MBTL1NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985904-A | SUITABLE FOR COMBATING ANIMAL PESTS, PREFERABLY ARTHROPODS AND NEMATODES, AND IN PARTICULAR INSECTS AND ARACHNIDS, WHICH ARE ENCOUNTERED IN AGRICULTURE, IN FORESTRY, IN THE PROTECTION OF STORED PRODUCTS AND OF MATERIALS, AND IN THE HYGIENE FIELD | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-16 | — | — | US | claimed |
| EP-0740663-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR USE AS PARASITICIDES FOR ANIMALS | BAYER AG (DE) | 1996-11-06 | — | — | EP | claimed |
| WO-1995019353-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR USE AS PARASITICIDES FOR ANIMALS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-20 | — | — | WO | claimed |
| US-5985904-A | SUITABLE FOR COMBATING ANIMAL PESTS, PREFERABLY ARTHROPODS AND NEMATODES, AND IN PARTICULAR INSECTS AND ARACHNIDS, WHICH ARE ENCOUNTERED IN AGRICULTURE, IN FORESTRY, IN THE PROTECTION OF STORED PRODUCTS AND OF MATERIALS, AND IN THE HYGIENE FIELD | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-16 | — | — | US | disclosed |
| EP-0740663-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR USE AS PARASITICIDES FOR ANIMALS | BAYER AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019353-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR USE AS PARASITICIDES FOR ANIMALS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-20 | — | — | WO | disclosed |