Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 5/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488396 | 1.00 | IRAK4 (0.39) | IRAK4KDM4ECHRM4CYP3A4CYP2C9 | |
| SCHEMBL8487970 | 0.87 | IRAK4 (0.36) | IRAK4KDM4ECHRM4CYP3A4CYP2C9 | |
| SCHEMBL8487972 | 0.87 | IRAK4 (0.36) | IRAK4KDM4ECHRM4CYP3A4CYP2C9 | |
| SCHEMBL8488247 | 0.86 | IRAK4 (0.37) | IRAK4KDM4ECHRM4CYP3A4CYP2C9 | |
| SCHEMBL8766984 | 0.86 | IRAK4 (0.37) | IRAK4KDM4ECHRM4CYP3A4CYP2C9 | |
| SCHEMBL8486736 | 0.86 | IRAK4 (0.37) | IRAK4KDM4ECHRM4CYP3A4CYP2C9 | |
| SCHEMBL8767156 | 0.86 | IRAK4 (0.37) | IRAK4KDM4ECHRM4CYP3A4CYP2C9 | |
| SCHEMBL8766979 | 0.86 | IRAK4 (0.37) | IRAK4KDM4ECHRM4CYP3A4CYP2C9 | |
| SCHEMBL8486378 | 0.86 | IRAK4 (0.37) | IRAK4KDM4ECHRM4CYP3A4CYP2C9 | |
| SCHEMBL8767161 | 0.86 | IRAK4 (0.37) | IRAK4KDM4ECHRM4CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889012-A | INSECTICIDE, ACARICIDES, FUNGICIDES | HOECHST-SCHERING AGREVO GMBH (DE) | 1999-03-30 | — | — | US | disclosed |
| EP-0787128-A1 | SUBSTITUTED CYCLOALKYLAMINO AND CYCLOALKOXY HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996011913-A1 | SUBSTITUTED CYCLOALKYLAMINO AND CYCLOALKOXY HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-04-25 | — | — | WO | disclosed |