SCHEMBL8488488

SCHEMBL8488488

ClC(Cl)SC(Cl)Cl.Sc1ccc(Br)cc1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.38
IDO1 P14902 1/20 0.36
KDM1A O60341 1/20 0.31
ALDH1A1 P00352 2/20 0.31
ALOX15 P16050 2/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8488489 0.82 CYP2A6 (0.44) CYP2A6IDO1ALDH1A1ALOX15MAPK1
Hydrochloric Acid SCHEMBL28463775 0.82
SCHEMBL17193 0.79
Fluoride SCHEMBL28685325 0.76 CYP2A6 (0.57) CYP2A6IDO1ALDH1A1ALOX15MAPK1
SCHEMBL7739898 0.76
SCHEMBL6519009 0.76
SCHEMBL5314329 0.76
Water SCHEMBL28352869 0.76
Hydrogen Sulfide SCHEMBL27768236 0.76 CYP2A6 (0.57) CYP2A6IDO1ALDH1A1ALOX15MAPK1
SCHEMBL8484800 0.72 CYP2A6 (0.44) CYP2A6IDO1ALDH1A1ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5932731-A HYDROLYZING A HETEROAROMATIC HALOGENATED METHYL SULFIDE IN PRESENCE OF AN ACID SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1999-08-03 US disclosed