Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.32 |
| ▸ | SHBG | P04278 | 2/20 | 0.32 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488657 | 1.00 | TSHR (0.33) | TSHRNR1I3LMNAGPBAR1SHBG | |
| SCHEMBL9815688 | 0.92 | NR1I3 (0.40) | TSHRNR1I3LMNAGPBAR1SHBG | |
| SCHEMBL5240446 | 0.90 | NR1I3 (0.39) | TSHRNR1I3LMNAGPBAR1SHBG | |
| SCHEMBL8484507 | 0.87 | NR1I3 (0.38) | TSHRNR1I3LMNAGPBAR1SHBG | |
| SCHEMBL8484503 | 0.87 | NR1I3 (0.38) | TSHRNR1I3LMNAGPBAR1SHBG | |
| SCHEMBL9132252 | 0.85 | — | — | |
| SCHEMBL9132244 | 0.85 | — | — | |
| SCHEMBL8977695 | 0.79 | NR1I3 (0.36) | TSHRNR1I3LMNAGPBAR1SHBG | |
| SCHEMBL21285226 | 0.74 | GBA1 (0.34) | NR1I3 | |
| SCHEMBL6836211 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889012-A | INSECTICIDE, ACARICIDES, FUNGICIDES | HOECHST-SCHERING AGREVO GMBH (DE) | 1999-03-30 | — | — | US | disclosed |
| EP-0787128-A1 | SUBSTITUTED CYCLOALKYLAMINO AND CYCLOALKOXY HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996011913-A1 | SUBSTITUTED CYCLOALKYLAMINO AND CYCLOALKOXY HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-04-25 | — | — | WO | disclosed |