Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.80 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.80 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.80 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.80 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13243429 | 0.95 | CHRM1 (0.88) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL3003287 | 0.95 | CHRM1 (0.88) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL13243457 | 0.95 | CHRM1 (0.88) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL6580373 | 0.89 | CHRM1 (1.00) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL4669587 | 0.86 | CHRM1 (0.91) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL13243458 | 0.85 | CHRM1 (0.70) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL3411560 | 0.85 | CHRM1 (0.70) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL3000147 | 0.84 | CHRM1 (0.70) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL2998817 | 0.83 | CHRM1 (0.68) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL2998805 | 0.83 | CHRM1 (0.68) | CHRM1CHRM2CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032481-A1 | MUSCARINIC AGENTS AND USE THEREOF TO TREAT GLAUCOMA, MYOPIA AND VARIOUS OTHER CONDITIONS | ALCON LABORATORIES, INC. (US) | 1999-07-01 | — | — | WO | disclosed |